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Sunday, 29 November 2020
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It's hard to believe that the UK government did not know this
it's hard to believe that the UK government did not know this as schoolchildren are well known as asymptomatic carriers of flu
Largest COVID-19 contact tracing study to date finds children key to spread, evidence of superspreaders
Sept. 30, 2020
A study of more than a half-million people in India who were exposed to the novel coronavirus SARS-CoV-2 suggests that the virus’ continued spread is driven by only a small percentage of those who become infected.
Furthermore, children and young adults were found to be potentially much more important to transmitting the virus — especially within households — than previous studies have identified, according to a paper by researchers from the United States and India published Sept. 30 in the journal Science.
Researchers from the Princeton Environmental Institute (PEI), Johns Hopkins University and the University of California, Berkeley, worked with public health officials in the southeast Indian states of Tamil Nadu and Andhra Pradesh to track the infection pathways and mortality rate of 575,071 individuals who were exposed to 84,965 confirmed cases of COVID-19, the disease caused by SARS-CoV-2. It is the largest contact tracing study — which is the process of identifying people who came into contact with an infected person — conducted in the world for any disease.
Lead researcher Ramanan Laxminarayan, a senior research scholar in PEI, said that the paper is the first large study to capture the extraordinary extent to which SARS-CoV-2 hinges on “superspreading,” in which a small percentage of the infected population passes the virus on to more people. The researchers found that 71% of infected individuals did not infect any of their contacts, while a mere 8% of infected individuals accounted for 60% of new infections.
“Our study presents the largest empirical demonstration of superspreading that we are aware of in any infectious disease,” Laxminarayan said. “Superspreading events are the rule rather than the exception when one is looking at the spread of COVID-19, both in India and likely in all affected places.”
The findings provide extensive insight into the spread and deadliness of COVID-19 in countries such as India — which has experienced more than 96,000 deaths from the disease — that have a high incidence of resource-limited populations, the researchers reported. They found that coronavirus-related deaths in India occurred, on average, six days after hospitalization compared to an average of 13 days in the United States. Also, deaths from coronavirus in India have been concentrated among people aged 50-64, which is slightly younger than the 60-plus at-risk population in the United States.
The researchers also reported, however, the first large-scale evidence that the implementation of a countrywide shutdown in India led to substantial reductions in coronavirus transmission.
The researchers found that the chances of a person with coronavirus, regardless of their age, passing it on to a close contact ranged from 2.6% in the community to 9% in the household. The researchers found that children and young adults — who made up one-third of COVID cases — were especially key to transmitting the virus in the studied populations.
“Kids are very efficient transmitters in this setting, which is something that hasn’t been firmly established in previous studies,” Laxminarayan said. “We found that reported cases and deaths have been more concentrated in younger cohorts than we expected based on observations in higher-income countries.”
Children and young adults were much more likely to contract coronavirus from people their own age, the study found. Across all age groups, people had a greater chance of catching the coronavirus from someone their own age. The overall probability of catching coronavirus ranged from 4.7% for low-risk contacts up to 10.7% for high-risk contacts.
The study, “Epidemiology and transmission dynamics
of COVID-19 in two Indian states,” was published Sept. 30 by the journal
Science. The work was supported by the National Science Foundation and
the Centers for Disease Control and Prevention.
Tuesday, 17 November 2020
Monday, 16 November 2020
WARNING CREDIT CARD SCAM - Mastercard and Visa cards
WARNING CREDIT CARD SCAM - Mastercard and Visa cards
Monday, 9 November 2020
Status of COVID-19: As of 19 March 2020, COVID-19 is no longer considered to be a high consequence infectious disease (HCID) in the UK.
Status of COVID-19
As of 19 March 2020, COVID-19 is no longer considered to be a high consequence infectious disease (HCID) in the UK.
The 4 nations public health HCID group made an interim recommendation in January 2020 to classify COVID-19 as an HCID. This was based on consideration of the UK HCID criteria about the virus and the disease with information available during the early stages of the outbreak. Now that more is known about COVID-19, the public health bodies in the UK have reviewed the most up to date information about COVID-19 against the UK HCID criteria. They have determined that several features have now changed; in particular, more information is available about mortality rates (low overall), and there is now greater clinical awareness and a specific and sensitive laboratory test, the availability of which continues to increase.
The Advisory Committee on Dangerous Pathogens (ACDP) is also of the opinion that COVID-19 should no longer be classified as an HCID.
The need to have a national, coordinated response remains, but this is being met by the government’s COVID-19 response.
Cases of COVID-19 are no longer managed by HCID treatment centres only. All healthcare workers managing possible and confirmed cases should follow the updated national infection and prevention (IPC) guidance for COVID-19, which supersedes all previous IPC guidance for COVID-19. This guidance includes instructions about different personal protective equipment (PPE) ensembles that are appropriate for different clinical scenarios.
Definition of HCID
In the UK, a high consequence infectious disease (HCID) is defined according to the following criteria:
- acute infectious disease
- typically has a high case-fatality rate
- may not have effective prophylaxis or treatment
- often difficult to recognise and detect rapidly
- ability to spread in the community and within healthcare settings
- requires an enhanced individual, population and system response to ensure it is managed effectively, efficiently and safely
Classification of HCIDs
HCIDs are further divided into contact and airborne groups:
contact HCIDs are usually spread by direct contact with an infected patient or infected fluids, tissues and other materials, or by indirect contact with contaminated materials and fomites
-
airborne HCIDs are spread by respiratory droplets or aerosol transmission, in addition to contact routes of transmission
List of high consequence infectious diseases
A list of HCIDs has been agreed by a joint Public Health England (PHE) and NHS England HCID Programme:
| Contact HCID | Airborne HCID |
|---|---|
| Argentine haemorrhagic fever (Junin virus) | Andes virus infection (hantavirus) |
| Bolivian haemorrhagic fever (Machupo virus) | Avian influenza A H7N9 and H5N1 |
| Crimean Congo haemorrhagic fever (CCHF) | Avian influenza A H5N6 and H7N7 |
| Ebola virus disease (EVD) | Middle East respiratory syndrome (MERS) |
| Lassa fever | Monkeypox |
| Lujo virus disease | Nipah virus infection |
| Marburg virus disease (MVD) | Pneumonic plague (Yersinia pestis) |
| Severe fever with thrombocytopaenia syndrome (SFTS) | Severe acute respiratory syndrome (SARS)* |
*No cases reported since 2004, but SARS remains a notifiable disease under the International Health Regulations (2005), hence its inclusion here
**Human to human transmission has not been described to date for
avian influenza A(H5N6). Human to human transmission has been described
for avian influenza A(H5N1), although this was not apparent until more
than 30 human cases had been reported. Both A(H5N6) and A(H5N1) often
cause severe illness and fatalities. Therefore, A(H5N6) has been
included in the airborne HCID list despite not meeting all of the HCID criteria.
The list of HCIDs will be kept under review and updated by PHE if new HCIDs emerge that are of relevance to the UK.
HCIDs in the UK
HCIDs, including viral haemorrhagic fevers (VHFs), are rare in the UK. When cases do occur, they tend to be sporadic and are typically associated with recent travel to an area where the infection is known to be endemic or where an outbreak is occurring. None of the HCIDs listed above are endemic in the UK, and the known animal reservoirs are not found in the UK.
As of February 2020, 2019, the UK has experience of managing confirmed cases of Lassa fever, EVD, CCHF, MERS
and monkeypox. The vast majority of these patients acquired their
infections overseas, but rare incidents of secondary transmission of MERS and monkeypox have occurred in the UK.
https://www.gov.uk/guidance/high-consequence-infectious-diseases-hcid?fbclid=IwAR1WvHvkce7fl-rS-nWM2_V1gh45aQn52yaXb4ZV2xUeHuNyRjSY3NTjbhg
